10 Drugs That May Cause Memory Loss

by Dr. Armon B. Neel Jr., AARP, June 9, 2015

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M ost people are familiar with at least some of the things that can impair memory, including alcohol and drug abuse, heavy cigarette smoking, head injuries, stroke, sleep deprivation, severe stress, vitamin B12 deficiency, and illnesses such as Alzheimer's disease and depression.

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woman
Forgetful? Your prescription meds could be interfering with your memory. — Larry Williams/Corbis
But what many people don't realize is that many commonly prescribed drugs also can interfere with memory. Here are 10 of the top types of offenders. The good news is that the memory loss from medications can often be relieved by stopping the medication, lowering the dose or using an alternative treatment.

1. Antianxiety drugs
(Benzodiazepines)

Why they are prescribed: Benzodiazepines are used to treat a variety of anxiety disorders, agitation, delirium and muscle spasms, and to prevent seizures. Because benzodiazepines have a sedative effect, they are sometimes used to treat insomnia and the anxiety that can accompany depression.

Examples:
Alprazolam (Xanax), chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Valium), flurazepam (Dalmane), lorazepam (Ativan), midazolam (Versed), quazepam (Doral), temazepam (Restoril) and triazolam (Halcion).

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Alternatives:
    Drugs that May
   Cause Memory Loss

  1. Antianxiety drugs
  2. Cholesterol drugs
  3. Antiseizure drugs
  4. Antidepressant drugs
  5. Narcotic painkillers
  6. Parkinson's drugs
  7. Hypertension drugs
  8. Sleeping aids
  9. Incontinence drugs
  10. Antihistamines
Benzodiazepines should be prescribed only rarely in older adults, in my judgment, and then only for short periods of time. It takes older people much longer than younger people to flush these drugs out of their bodies, and the ensuing buildup puts older adults at higher risk for not just memory loss, but delirium, falls, fractures and motor vehicle accidents.

If you take one of these meds for insomnia, mild anxiety or agitation, talk with your doctor or other health care professional about treating your condition with other types of drugs or nondrug treatments. If you have insomnia, for instance, melatonin might help. Taken before bedtime in doses from 3 to 10 mg, melatonin can help to reestablish healthy sleep patterns.

Be sure to consult your health care professional before stopping or reducing the dosage of any benzodiazepine. Sudden withdrawal can trigger serious side effects, so a health professional should always monitor the process.

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